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American Ethnologist: Vol. 32, No. 2Editor's Foreword - Virginia R. Dominguez
Experimenting, improvising, compromising, and intervening?
These words appear on the front cover of this issue as well as in the expanded versions of the titles given to the subgroupings I have created (“Experimenting with Ethics, Experimenting as Science,” “Improvising in and through Music,” “Compromising Sovereignty or Modeling It?” and “Intervening in Intimacy”). I intend both the dynamism that these verb forms convey and the built-in ambiguity of not specifying who is experimenting, who is improvising, who is compromising, and who is intervening. The groupings in this issue demand that we as readers ask who is doing what to whom and that we notice ambiguity and even productive tension.
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Table of Contents for AE, Vol. 32, No. 2
Table of Contents
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Abstracts from AE Vol. 32, No. 2
Experimenting with Ethics, Experimenting as Science
Ethical variability: Drug development and globalizing clinical trials
Adriana Petryna
The rapid growth of pharmaceutical markets has led to increased demands for human subjects for drug research, particularly in low-income countries. For regulatory, economic, and even biological reasons, new populations are being pursued as human subjects for pharmaceutical trials. In this article I consider the evolution of commercialized clinical trials and ethical and regulatory environments as they contribute to a dramatic growth of human-subjects involvement in research. I focus on the operations of U.S.-based contract research organizations (CROs), which make up a specialized global industry focusing on human-subjects recruitment and research and the on ways in which they expedite drug testing to low-income contexts. Specifically, I analyze how these transstate actors interact with regulatory authorities in the United States and how they recast international ethical guidelines as they organize trials for research subjects abroad. [global pharmaceuticals, bioethics, clinical trials, human subjects, research ethics, governance, biological citizenship]
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